Blueberry muffin rash congenital rubella syndrome

These are due to the presence of clusters of blood-producing cells in the skin (extramedullary erythropoiesis), or bleeding into the skin (purpura) or spreading cancer (metastases). The baby had blueberry muffin skin lesions, long bone metaphysitis and congenital heart defects. With this case report we would like to highlight the existence of congenital rubella syndrome.

The case of a preterm neonate with blueberry muffin lesions and classical as well as rare systemic features of congenital rubella syndrome is reported. Blueberry muffin baby is the characteristic distributed purpura occurring as a result of extramedullary hematopoiesis found in infants. The purpura are often generalize but occur more often on the trunk, hea and neck.

If infection occurs 0–days before conception, the infant has a risk of being affected. Without the history above, the appearance of the rash alone would lead me to consider the blueberry muffin rash characteristic of congenital rubella syndrome (CRS). However, CRS is rare in the United States and in other developed countries with high uptake of childhood vaccination.

A diagnosis of blueberry muffin rash in a child with congenital rubella syndrome was made based on the clinical and laboratory findings. The rash disappeared by weeks of life. These children had generalized hemorrhagic purpuric eruptions that on histopathology showed dermal erythropoiesis.

Since then, congenital infections comprising the TORCH syndrome (toxoplasmosis, other, rubella , cytomegalovirus, herpes) and hematologic dyscrasias have classically been associated with blueberry muffin -like lesions. These entities should be ruled out by history, evaluation. Triad of congenital rubella syndrome.

Cataracts: Other eye manifestations may also occur later in life (e.g., salt and pepper retinopathy, glaucoma). This makes TORCH infections less likely, but not impossible. The clinical presentation and investigations of this neonate were suggestive of Gregg syndrome (CRS) with blueberry muffin rash and congenital cataract, which is a very rare condition with an annual incidence of 0. Blueberry Muffin Rash Treatment Blueberry muffin rash involves various causes so, treatment is selected according to them.

Physicians recommend to manage the leading cause 1st and ultimately blueberry muffin rash heals itself. In case of congenital diseases, there is no permanent treatment but temporary treatment can remove blueberry muffin rash. Please Note: You may not embed one of our images on your web page without a link back to our site. If you would like a large, unwatermarked image for your web page or blog, please purchase the appropriate license.

If such an infection does not lead to miscarriage or still birth, the neonate may show severe congenital malformations. The molecular basis for the causation of congenital rubella syndrome are not yet completely clear, but in. Blueberry muffin rash Thrombocytopenic Purpura Other name(s) for Erythema Infectious. Congenital Rubella Syndrome. Fifth Disease Slap Cheek.

Y=Yes N=No U=Unknown Division of Infectious Disease Epidemiology rev09. CMV is the most common, non-genetic cause of childhood hearing loss. Cytomegalovirus is the leading cause of congenital infections wordwide. Likely non-viable, but mother and father should be involved in the decision to forego support.

A baby with a congenital cataract and blueberry muffin rash – classic signs of congenital rubella syndrome.

CC BY-NC-SA) (CC BY-NC-SA) In addition to respiratory problems (think iron lungs), polio causes muscle atrophy. Anything that appears in red is not available for data entry into NEDSS. However, you may find those fields help-ful in your investigation.

Notify Central Office Immunization Program regarding this case.