Rubella effects on fetus

How does rubella affect developing fetus? What are the long term effects of rubella? Will rubella affect an unborn baby? Can codeine harm an unborn fetus?

Fetal rubella effects : The constellation of abnormalities, also called the rubella syndrome, caused by infection with the rubella (German measles) A virus before birth.

The syndrome is characterized by multiple congenital malformations (birth defects) and mental retardation. If infection occurs 0–days before conception, the infant has a risk of being affected. Pregnant women who contract rubella are at risk for miscarriage or stillbirth, and their developing babies are at risk for severe birth defects with devastating, lifelong consequences. Congenital rubella can have very serious implications for an unborn baby. Effects of rubella virus on the human fetus.

Human fibroblasts infected with rubella virus produce a growth inhibitor. The highest risk to the fetus is during the first trimester, but exposure later in pregnancy also is dangerous. The rubella vaccine is usually given as a combined measles-mumps-rubella inoculation, which contains the safest and most effective form of each vaccine.

Depending on the gestational period when the mother contracts rubella , an infant born with CRS may be unaffected by the virus or it may have severe developmental defects. A rubella infection can cause miscarriage, preterm birth, or stillbirth, as well as a variety of birth defects, but it depends on how far along you are when you contract the virus. Rubella virus viremia can infect the placenta of pregnant women, and viral replication can infect all fetal organs. In tissue specimens, infections with rubella virus have diverse effects , ranging from small foci of infected cells in apparently normal tissue to hypoplasia, generalized vasculitis, and cell destruction.

Rubella can be a serious threat to your pregnancy, especially during the first and second trimesters. Studies of affected infants born in Philadelphia, U. Rubella during pregnancy, its effects upon perinatal mortality, the incidence of congenital abnormalities and immaturity. In rare cases, rubella can cause serious problems, including brain infections and bleeding problems. The most serious complication from rubella infection is the harm it can cause a pregnant woman’s developing baby.

If an unvaccinated pregnant woman gets infected with rubella virus she can have a miscarriage, or her baby can die just after birth. Rubella has symptoms that are similar to those of flu. However, the primary symptom of rubella virus infection is the appearance of a rash (exanthem) on the face which spreads to the trunk and limbs and usually fades after three days (that is why it is often referred to as three-day measles).

Rubella is the R in the TORCHeS mnemonic for congenital infections. It can cause severe problems for the fetus if a woman is infected during pregnancy. However, rubella is still common in many developing countries.

National uptake of antenatal screening for rubella susceptibility fell slightly from 98. Catching rubella during the first five months of pregnancy is extremely dangerous for the unborn baby.

In approximately of cases in which the woman contracts rubella during pregnancy, the fetus will become sick. The earlier that the unborn baby is exposed to rubella , the more severely she is likely to be affected. Maternal rubella infection is generally asymptomatic or a mild flu-like illness of malaise, headache, coryza and lymphadenopathy, followed by a diffuse, fine maculopapular rash.

In contrast, the effects on the fetus can be devastating if infected in the first trimester. This disease can be prevented by the administration of the MMR (measles-mumps- rubella ) vaccine that is generally given to children before they start school.